Ankylosing Spondylitis,  ArthritiCare,  Arthritis Care,  Arthritis News,  Arthritis Pain,  Autoimmune Arthritis,  Juvenile Idiopathic (JIA),  Lupus-Related Arthritis,  Psoriatic Arthritis,  Rheumatoid Arthritis (RA)

Autoimmune Arthritis: A Comprehensive List of 21 types of including video’s and full reports:

Here’s a comprehensive list of various types of autoimmune arthritis and related conditions along with detailed information:

  1. Rheumatoid Arthritis (RA)
    • Description: Chronic autoimmune disease primarily affecting joints, causing inflammation, pain, and joint damage.
    • Major Symptoms:
      • Joint pain, swelling, and stiffness
      • Fatigue
      • Morning stiffness lasting more than 30 minutes
      • Symmetrical joint involvement (e.g., both hands, wrists)
    • Causes: Genetic predisposition, environmental factors (e.g., smoking, infections).
    • Minor Symptoms:
      • Fever
      • Loss of appetite
      • Nodules under the skin
    • Major Causes: Autoimmune response targeting joint tissues.
    • Triggers: Infections, hormonal changes, stress.
    • Joint/Motion Affected: Small joints of hands and feet, wrists, elbows, knees.
    • Remission Chances: Achievable with early and aggressive treatment in some cases.
    • Average Age of Early Onset: 30-50 years.
    • Gender Affected: More common in women.
    • Related Diseases/Conditions: Increased risk of cardiovascular diseases, osteoporosis.
    • Complications: Joint deformity, disability.
    • Autoimmune Type: Yes.
    • Life Expectancy Impact: May reduce life expectancy due to associated conditions.
    • Learn more on Rheumatoid
  2. Juvenile Idiopathic Arthritis (JIA)

    • Description: Chronic arthritis of unknown cause that begins before age 16, with various subtypes.
    • Major Symptoms: Joint pain, swelling, stiffness, fever, limited motion.
    • Causes: Combination of genetic and environmental factors triggering immune system dysfunction.
    • Minor Symptoms: Rash, eye inflammation (uveitis), growth problems.
    • Major Causes: Autoimmune reaction affecting joints.
    • Triggers: Infections, genetics.
    • Joint/Motion Affected: Variable; may involve any joint, including knees, wrists, ankles.
    • Remission Chances: Varies by subtype and individual response to treatment.
    • Average Age of Early Onset: Childhood.
    • Gender Affected: Both sexes, varies by subtype.
    • Related Diseases/Conditions: Uveitis, growth disturbances.
    • Complications: Joint damage, growth problems, eye complications.
    • Autoimmune Type: Yes.
    • Life Expectancy Impact: Generally less severe compared to adult-onset arthritis.
    • Learn more on Juvenile Idiopathic Arthritis
  3. Psoriatic Arthritis (PsA)
    • Description: Inflammatory arthritis associated with psoriasis, affecting joints and skin.
    • Major Symptoms:
      • Joint pain, stiffness, swelling
      • Skin patches (psoriasis plaques)
      • Nail changes (pitting, thickening)
      • Enthesitis (inflammation where tendons/ligaments insert into bones)
    • Causes: Genetic predisposition, triggered by immune response to psoriasis.
    • Minor Symptoms: Fatigue, eye inflammation (uveitis).
    • Major Causes: Autoimmune process linked to psoriasis.
    • Triggers: Stress, skin injury, infections.
    • Joint/Motion Affected: Joints of hands, feet, spine (spondylitis).
    • Remission Chances: Possible with treatment, but variable.
    • Average Age of Early Onset: 30-50 years.
    • Gender Affected: Equal incidence in men and women.
    • Related Diseases/Conditions: Psoriasis, inflammatory bowel disease.
    • Complications: Joint damage, eye problems, cardiovascular disease.
    • Autoimmune Type: Yes.
    • Life Expectancy Impact: Generally manageable with treatment; impact on life expectancy varies.
    • Learn more on Psoriatic Arthritis
  4. Ankylosing Spondylitis (AS)
    • Description: Chronic inflammatory arthritis affecting the spine and sacroiliac joints.
    • Major Symptoms:
      • Back pain, stiffness (worse in the morning)
      • Reduced spinal mobility
      • Enthesitis (inflammation of tendons/ligaments)
      • Fatigue
    • Causes: Strong genetic component (HLA-B27 gene), triggered by environmental factors.
    • Minor Symptoms: Peripheral joint involvement, eye inflammation (uveitis).
    • Major Causes: Autoimmune mechanism targeting spine and joints.
    • Triggers: Infections (especially gastrointestinal), mechanical stress.
    • Joint/Motion Affected: Spine, sacroiliac joints, peripheral joints.
    • Remission Chances: Varies; early diagnosis and treatment can slowprogression.
    • Average Age of Early Onset: Typically before age 40.
    • Gender Affected: More common and often more severe in men.
    • Related Diseases/Conditions: Uveitis, inflammatory bowel disease (IBD).
    • Complications: Spinal fusion (ankylosis), reduced lung function.
    • Autoimmune Type: Yes.
    • Life Expectancy Impact: May reduce life expectancy due to complications like cardiovascular disease and respiratory issues.
    • Learn more on Ankylosing Spondylitis
  5. Reactive Arthritis (ReA)
    • Description: Inflammatory arthritis occurring after certain infections, typically gastrointestinal or genitourinary.
    • Major Symptoms:
      • Asymmetric joint pain, swelling (especially knees, ankles)
      • Eye inflammation (conjunctivitis, uveitis)
      • Genitourinary symptoms (urethritis, cervicitis)
      • Skin rash
    • Causes: Immune response triggered by bacterial infections (e.g., Chlamydia, Salmonella).
    • Minor Symptoms: Fatigue, fever, mouth ulcers.
    • Major Causes: Post-infectious autoimmune reaction.
    • Triggers: Bacterial infections.
    • Joint/Motion Affected: Lower extremities (knees, ankles), sacroiliac joints.
    • Remission Chances: Can resolve on its own, but some cases become chronic.
    • Average Age of Early Onset: Adults under 40 years.
    • Gender Affected: Men more commonly affected.
    • Related Diseases/Conditions: Inflammatory bowel disease (IBD), eye complications.
    • Complications: Chronic joint inflammation, persistent symptoms.

  1. Enteropathic Arthritis (Associated with Inflammatory Bowel Disease)
    • Description: Arthritis linked to inflammatory bowel diseases (Crohn’s disease, ulcerative colitis).
    • Major Symptoms:
      • Peripheral joint pain, swelling
      • Abdominal pain (related to bowel inflammation)
      • Diarrhea, weight loss
      • Fatigue
    • Causes: Immune system response to gut inflammation.
    • Minor Symptoms: Skin lesions, eye inflammation.
    • Major Causes: Autoimmune process related to bowel disease.
    • Triggers: Flare-ups of inflammatory bowel disease.
    • Joint/Motion Affected: Peripheral joints, spine.
    • Remission Chances: Linked to control of underlying bowel disease.
    • Average Age of Early Onset: Varies; often coincides with bowel disease diagnosis.
    • Gender Affected: Both sexes equally affected.
    • Related Diseases/Conditions: Inflammatory bowel disease (Crohn’s, UC), uveitis.
    • Complications: Joint damage, bowel complications.
    • Learn more: Enteropathic Arthritis
  2. Undifferentiated Spondyloarthritis
    • Description: Inflammatory arthritis resembling spondyloarthritis but not meeting specific criteria for other subtypes.
    • Major Symptoms: Back pain, peripheral joint involvement, enthesitis.
    • Causes: Genetic susceptibility, immune dysregulation.
    • Minor Symptoms: Eye inflammation, skin involvement.
    • Major Causes: Autoimmune process affecting joints and spine.
    • Triggers: Infections, genetic factors.
    • Joint/Motion Affected: Variable; may resemble features of AS or PsA.
    • Remission Chances: Varies; depends on disease course.
    • Average Age of Early Onset: Young adulthood.
    • Gender Affected: Both sexes equally affected.
    • Related Diseases/Conditions: Uveitis, inflammatory bowel disease (IBD).
    • Complications: Joint damage, disability.
  3. Systemic Lupus Erythematosus (SLE)
    • Description: Systemic autoimmune disease affecting multiple organs, including joints.
    • Major Symptoms:
      • Joint pain, stiffness (often migratory)
      • Skin rash (butterfly rash)
      • Fatigue, fever
      • Kidney, heart, or lung involvement
    • Causes: Genetic and environmental factors triggering immune response.
    • Minor Symptoms: Hair loss, mouth/nasal ulcers, photosensitivity.
    • Major Causes: Autoantibodies targeting tissues and organs.
    • Triggers: Sun exposure, infections, hormonal changes.
    • Joint/Motion Affected: Small and large joints.
    • Remission Chances: Variable; periods of remission and flare-ups.
    • Average Age of Early Onset: Childbearing age (15-44 years).
    • Gender Affected: Women more commonly affected.
    • Related Diseases/Conditions: Kidney disease (lupus nephritis), cardiovascular disease.
    • Complications: Organ damage, increased risk of infections.
    • Autoimmune Type: Yes.
    • Life Expectancy Impact: May reduce life expectancy if major organ involvement occurs.
    • Learn more on Lupus Arthritis
  4. Sjögren’s Syndrome
    • Description: Autoimmune disorder affecting moisture-producing glands (salivary, tear).
    • Major Symptoms:
      • Dry eyes, dry mouth
      • Joint pain, stiffness
      • Fatigue
      • Salivary gland enlargement, dental caries
    • Causes: Autoimmune attack on exocrine glands.
    • Minor Symptoms: Skin rashes, lung involvement (interstitial lung disease).
    • Major Causes: Autoimmune dysfunction.
    • Triggers: Genetic predisposition, viral infections.
    • Joint/Motion Affected: Small joints, large joints.
    • Remission Chances: Varies; symptom management is mainstay of treatment.
    • Average Age of Early Onset: 40-60 years.
    • Gender Affected: Women more commonly affected.
    • Related Diseases/Conditions: Increased risk of lymphoma, vasculitis.
    • Complications: Dryness-related complications (e.g., dental issues, eye damage).
    • Learn more on Sjögren’s Syndrome
  5. Mixed Connective Tissue Disease (MCTD)
    • Description: Overlap syndrome featuring characteristics of multiple connective tissue diseases.
    • Major Symptoms:
      • Joint pain, swelling
      • Raynaud’s phenomenon (cold-induced color changes in fingers/toes)
      • Muscle weakness
      • Skin changes (scleroderma-like, lupus-like)
    • Causes: Unknown; autoimmune etiology.
    • Minor Symptoms: Heartburn, difficulty swallowing.
    • Major Causes: Autoantibodies targeting various tissues.
    • Triggers: Unknown; likely genetic and environmental factors.
    • Joint/Motion Affected: Variable; resembles features of lupus, scleroderma, and other connective tissue diseases.
    • Remission Chances: Varies; depends on disease course.
    • Average Age of Early Onset: 20-40 years.
    • Gender Affected: Women more commonly affected.
    • Related Diseases/Conditions: Pulmonary hypertension, interstitial lung disease.
    • Complications: Organ involvement (e.g., pulmonary, cardiac).
    • Learn more on Mixed Connective Tissue Disease
  6. Systemic Sclerosis (Scleroderma)
    • Description: Chronic autoimmune disease characterized by excessive collagen production, leading to skin thickening and internal organ involvement.
    • Major Symptoms:
      • Thickening and hardening of skin (scleroderma)
      • Raynaud’s phenomenon (fingers/toes turn white/blue in response to cold)
      • Esophageal dysfunction (acid reflux, difficulty swallowing)
      • Joint pain and stiffness
    • Causes: Autoimmune process causing abnormal collagen deposition.
    • Minor Symptoms:
      • Respiratory symptoms (shortness of breath, cough)
      • Kidney involvement (hypertension, renal crisis)
      • Digital ulcers
    • Major Causes: Autoimmunity targeting connective tissues.
    • Triggers: Unknown; genetic and environmental factors.
    • Joint/Motion Affected: Limited joint involvement; more prominent skin and internal organ involvement.
    • Remission Chances: Variable; focus on symptom management and organ-specific treatments.
    • Average Age of Early Onset: 30-50 years.
    • Gender Affected: Women more commonly affected.
    • Related Diseases/Conditions: Pulmonary hypertension, interstitial lung disease.
    • Complications: Organ involvement (heart, lungs, kidneys), increased risk of infections.
    • Autoimmune Type: Yes.
    • Life Expectancy Impact: Variable; depends on extent of organ involvement.
    • Learn more on Systemic Sclerosis
  7. Polymyositis/Dermatomyositis
    • Description: Inflammatory diseases affecting muscles (polymyositis) and skin/muscles (dermatomyositis).
    • Major Symptoms:
      • Muscle weakness (proximal muscles like shoulders, hips)
      • Skin rash (heliotrope rash, Gottron’s papules)
      • Difficulty swallowing (dysphagia)
      • Fatigue
    • Causes: Autoimmune process targeting muscles and skin.
    • Minor Symptoms:
      • Joint pain
      • Interstitial lung disease
      • Cardiac involvement (myocarditis)
    • Major Causes: Autoimmune attack on muscle and skin tissues.
    • Triggers: Unknown; likely combination of genetic and environmental factors.
    • Joint/Motion Affected: Proximal muscles (shoulders, hips), can involve small joints.
    • Remission Chances: Variable; aggressive treatment can induce remission.
    • Average Age of Early Onset: Adults, but can occur in children.
    • Gender Affected: Both sexes, slightly more common in women.
    • Related Diseases/Conditions: Interstitial lung disease, malignancy.
    • Complications: Muscle weakness leading to disability, respiratory failure.
    • Autoimmune Type: Yes.
    • Life Expectancy Impact: Depends on extent of muscle and organ involvement; can be reduced in severe cases.
    • Learn more on: Polymyositis
  8. Granulomatosis with Polyangiitis (Wegener’s Granulomatosis)
    • Description: Rare autoimmune disease characterized by inflammation of blood vessels (vasculitis) and formation of granulomas.
    • Major Symptoms:
      • Upper respiratory tract involvement (sinusitis, nosebleeds)
      • Lung involvement (cough, shortness of breath)
      • Kidney disease (glomerulonephritis)
      • Skin manifestations (purpura, ulcers)
    • Causes: Autoimmune attack on blood vessels.
    • Minor Symptoms:
      • Eye inflammation
      • Joint pain
      • Neurological symptoms (peripheral neuropathy)
    • Major Causes: Autoimmunity targeting small to medium-sized blood vessels.
    • Triggers: Genetic predisposition, environmental factors.
    • Joint/Motion Affected: Variable; joint pain and inflammation.
    • Remission Chances: Achievable with immunosuppressive therapy.
    • Average Age of Early Onset: Typically middle-aged adults.
    • Gender Affected: Slightly more common in men.
    • Related Diseases/Conditions: Kidney failure, lung complications.
    • Complications: Organ damage (kidney, lungs, nerves), increased risk of infections.
    • Autoimmune Type: Yes.
    • Life Expectancy Impact: Can be reduced due to severe organ involvement.
    • Learn more on Wegener’s Granulomatosis
  9. Microscopic Polyangiitis
    • Description: Necrotizing vasculitis affecting small blood vessels, often involving the kidneys, lungs, and skin.
    • Major Symptoms:
      • Kidney disease (glomerulonephritis)
      • Lung involvement (cough, shortness of breath)
      • Skin lesions (purpura, ulcers)
      • Nerve damage (peripheral neuropathy)
    • Causes: Autoimmune process leading to blood vessel inflammation.
    • Minor Symptoms:
      • Joint pain
      • Fever
      • Fatigue
    • Major Causes: Autoimmunity targeting small blood vessels.
    • Triggers: Genetic predisposition, environmental factors.
    • Joint/Motion Affected: Joint pain and inflammation.
    • Remission Chances: Possible with aggressive immunosuppressive treatment.
    • Average Age of Early Onset: Middle-aged adults.
    • Gender Affected: Both sexes, slightly more common in men.
    • Related Diseases/Conditions: Kidney failure, pulmonary hemorrhage.
    • Complications: Organ damage (kidneys, lungs, nerves), increased risk of infections.
    • Autoimmune Type: Yes.
    • Life Expectancy Impact: Can be reduced due to severe organ involvement.
    • Learn more on Microscopic Polyangiitis
  10. Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss Syndrome)
    • Description: Rare vasculitis involving blood vessels, often with asthma and elevated eosinophils.
    • Major Symptoms:
      • Asthma exacerbation
      • Sinusitis, nasal polyps
      • Peripheral neuropathy
      • Skin rash, purpura
    • Causes: Autoimmune vasculitis with eosinophilic infiltration.
    • Minor Symptoms:
      • Joint pain
      • Fatigue
      • Abdominal pain
    • Major Causes: Autoimmunity with eosinophilic inflammation.
    • Triggers: Unknown; may involve genetic and environmental factors.
    • Joint/Motion Affected: Joint pain and inflammation.
    • Remission Chances: Achievable with immunosuppressive therapy.
    • Average Age of Early Onset: Middle-aged adults.
    • Gender Affected: Both sexes.
    • Related Diseases/Conditions: Asthma, lung complications.
    • Complications: Organ damage (heart, lungs, nerves), increased risk of infections.
    • Autoimmune Type: Yes.
    • Life Expectancy Impact: Can be reduced in severe cases with organ involvement.
    • Learn more on Eosinophilic Granulomatosis with Polyangiitis
  11. Giant Cell Arteritis (Temporal Arteritis)
    • Description: Vasculitis affecting large arteries, commonly involving the temporal arteries.
    • Major Symptoms:
      • Severe headache (temporal region)
      • Jaw pain with chewing (claudication)
      • Vision changes (blurred vision, sudden blindness)
      • Scalp tenderness
    • Causes: Autoimmune inflammation of large blood vessels.
    • Minor Symptoms:
      • Fatigue
      • Fever
      • Muscle pain and stiffness
    • Major Causes: Autoimmunity affecting large arteries.
    • Triggers: Genetic predisposition, unknown environmental triggers.
    • Joint/Motion Affected: Can involve joint pain and stiffness.
    • Remission Chances: Achievable with corticosteroid treatment.
    • Average Age of Early Onset: Typically over age 50.
    • Gender Affected: More common in women.
    • Related Diseases/Conditions: Increased risk of aortic aneurysm, stroke.
    • Complications: Visual impairment, aortic complications.
    • Autoimmune Type: Yes.
    • Life Expectancy Impact: Can be reduced due to complications like stroke.
    • Learn more on Giant Cell Arteritis
  12. Takayasu Arteritis
    • Description: Chronic inflammation of large arteries, particularly the aorta and its branches.
    • Major Symptoms:
      • Reduced pulse in arms or legs (pulselessness)
      • Arm or leg claudication
      • High blood pressure (hypertension)
      • Fatigue, fever
    • Causes: Autoimmune process affecting large blood vessels.
    • Minor Symptoms:
      • Joint pain and stiffness
      • Skin rash
      • Visual disturbances
    • Major Causes: Autoimmunity targeting large arteries.
    • Triggers: Unknown; likely genetic and environmental factors.
    • Joint/Motion Affected: Joint symptoms due to inflammation.
    • Remission Chances: Achievable with immunosuppressive therapy.
    • Average Age of Early Onset: Young adults, but can occur at any age.
    • Gender Affected: More common in women.
    • Related Diseases/Conditions: Aortic aneurysm, stroke.
    • Complications: Aortic complications, organ ischemia.
    • Autoimmune Type: Yes.
    • Life Expectancy Impact: Can be reduced due to cardiovascular complications.
    • Learn more on Takayasu Arteritis
  13. Behçet’s Disease
    • Description: Chronic multisystem inflammatory disorder characterized by oral and genital ulcers, skin lesions, and uveitis.
    • Major Symptoms:
      • Oral ulcers
      • Genital ulcers
      • Skin lesions (erythema nodosum, pseudofolliculitis)
      • Eye inflammation (uveitis)
    • Causes: Autoimmune vasculitis affecting blood vessels of all sizes.
    • Minor Symptoms:
      • Joint pain
      • Gastrointestinal symptoms (abdominal pain, diarrhea)
      • Neurological symptoms (headaches, meningitis)
    • Major Causes: Autoimmunity with vasculitis.
    • Triggers: Unknown; possibly genetic and environmental factors.
    • Joint/Motion Affected: Joint pain and inflammation.
    • Remission Chances: Variable; treatment focuses on symptom management.
    • Average Age of Early Onset: Young adulthood.
    • Gender Affected: More common in men.
    • Related Diseases/Conditions: Eye complications, neurological involvement.
    • Complications: Blindness (from severe uveitis), neurological deficits.
    • Autoimmune Type: Yes.
    • Life Expectancy Impact: Depends on disease severity and complications.
    • Learn more on Behçet’s Disease
  14. Relapsing Polychondritis
    • Description: Rare autoimmune disease causing inflammation of cartilage throughout the body.
    • Major Symptoms:
      • Ear inflammation (auricular chondritis)
      • Nose cartilage inflammation (nasal chondritis)
      • Joint pain and swelling
      • Eye inflammation
    • Causes: Autoimmune attack on cartilage.
    • Minor Symptoms:
      • Respiratory symptoms (shortness of breath, cough)
      • Heart involvement
      • Skin lesions
    • Major Causes: Autoimmunity affecting cartilaginous structures.
    • Triggers: Unknown; likely genetic and environmental factors.
    • Joint/Motion Affected: Joint pain and inflammation due to cartilage involvement.
    • Remission Chances: Varies; focused on symptom management and immunosuppression.
    • Average Age of Early Onset: Middle-aged adults.
    • Gender Affected: More common in men.
    • Related Diseases/Conditions: Respiratory complications, cardiovascular involvement.
    • Complications: Cartilage destruction, respiratory compromise.
    • Autoimmune Type: Yes.
    • Life Expectancy Impact: Can be reduced in severe cases with organ involvement.
    • Learn more on Polychondritis
  15. Adult Onset Still’s Disease
    • Description: Systemic inflammatory disorder characterized by spiking fevers, rash, and joint pain.
    • Major Symptoms:
      • Persistent high fevers
      • Salmon-colored rash (evanescent)
      • Joint pain, typically involving wrists, knees
      • Sore throat
    • Causes: Autoimmune process with excessive cytokine production.
    • Minor Symptoms:
      • Fatigue
      • Enlarged spleen, lymph nodes
      • Muscle pain
    • Major Causes: Autoinflammatory response.
    • Triggers: Unknown; possibly viral or other infectious triggers.
    • Joint/Motion Affected: Predominantly joint pain and inflammation.
    • Remission Chances: Varies; some patients achieve remission with medications.
    • Average Age of Early Onset: Young adults, but can occur at any age.
    • Gender Affected: Equal incidence in men and women.
    • Related Diseases/Conditions: Reactive arthritis, serositis.
    • Complications: Joint destruction, systemic complications.
    • Autoimmune Type: Yes.
    • Life Expectancy Impact: Can be reduced in severe cases with organ involvement.
    • Learn more on Still’s Disease
  16. IgG4-Related Disease
    • Description: Immune-mediated fibroinflammatory condition affecting multiple organs.
    • Major Symptoms:
      • Enlarged organs (e.g., pancreas, salivary glands)
      • Lymphadenopathy (enlarged lymph nodes)
      • Sclerosing cholangitis (bile duct inflammation)
      • Retroperitoneal fibrosis
    • Causes: Abnormal immune response with IgG4-producing plasma cells.
    • Minor Symptoms:
      • Fatigue
      • Joint pain
      • Skin manifestations
    • Major Causes: Autoimmune process affecting various organs.
    • Triggers: Unknown; likely genetic and environmental factors.
    • Joint/Motion Affected: Joint pain and inflammation.
    • Remission Chances: Achievable with immunosuppressive therapy.
    • Average Age of Early Onset: Middle-aged adults.
    • Gender Affected: More common in men.
    • Related Diseases/Conditions: Pancreatitis, sclerosing diseases.
    • Complications: Organ damage (e.g., pancreatitis, kidney involvement).
    • Autoimmune Type: Yes.
    • Life Expectancy Impact: Variable; depends on organ involvement and response to treatment.
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